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Hasil cari dari kata atau frase: penicillin G (0.00994 detik)
Found 2 items, similar to penicillin G.
English → English (WordNet)
Definition: penicillin G
penicillin G
n : the penicillin that constitutes the principal component of
many commercial antibiotics [syn:
benzylpenicillin]
English → English (gcide)
Definition: penicillin G
penicillin
\pen`i*cil"lin\, n. [From Penicillium, the fungus
genus from which it was first isolated.] (Chem.)
Any of a variety of substances having a structure containing
a beta-lactam ring fused to a thiirane ring, to which a
carboxyl group is attached, most commonly referring to
benzyl penicillin. They are notable as powerful
antibacterial agents of relatively low toxicity which have
found extensive use in medicine for treating bacterial
infections. They are categorized as one of the classes of
beta-lactam antibiotic. They are produced naturally by some
fungi and bacteria, and industrial production processes
almost invariably start from some form of the penicillin
nucleus produced by fermentation of microorganisms. The
fermentation products are then chemically modified to produce
derivatives of enhanced potency, safety, or antibacterial
spectrum. The first penicillin to see extensive use
clinically (during World War II) was
penicillin G, also
called
benzypenicillin, and commonly simply
“penicillin”.
[PJC]
Note: [hand]The characteristic portion of the structure
characterizing a penicillin is the bicyclic structure
3,3-Dimethyl-7-oxo-4-thia-1-azabicylo[3.2.0]heptane-2-carboxylic
acid. The different penicillins have varying acyl
groups forming an amide bond with a nitrogen attached
to the 6-carbon of this nucleus. This distinguishes it
from the other classes of beta-lactam antibiotic, the
cephalosporins,
thienamycins and
sulfazecin.
[PJC]
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