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Hasil cari dari kata atau frase: Penicillinase(0.01203 detik)
Found 2 items, similar to Penicillinase.
English → English (WordNet)
n : enzyme produced by certain bacteria that inactivates
penicillin and results in resistance to that antibiotic
English → English (gcide)
Penicillinase \Pen`i*cil"lin*ase\, n. (Bioch.)
an enzyme which destroys the antibacterial activity of
penicillin by hydrolyzing the amide bond in the beta-lactam
ring. Many penicillinases are known, and are produced by a
wide variety of bacteria. The production of penicillinase is
one of the mechanisms by which bacteria may become resistant
to penicillins. Penicillinase production in various bacterial
species may be induced, i.e., it may occur only when
stimulated by the presence of penicillin in the culture
medium, or it may be constitutive, i.e., it may occur
whenever the cells are producing protein. Molecular weights
of the various penicillinases tend to cluster near 50,000.