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Hasil cari dari kata atau frase: C17H14O4S (0.00892 detik)
Found 1 items, similar to C17H14O4S.
English → English (gcide)
Definition: C17H14O4S
rofecoxib
\rofecoxib\ (Chem. & Med.)
A chemical substance (
C17H14O4S, molecular weight 314.36)
used in medicine as an analgesic to alleviate pain and
inflammation; it is a synthetic compound, and is marketed by
Merck & Co. under the trade name
Vioxx, in tablets giving
dosages of 12.5 or 25 milligrams. It is classed as a
non-steroidal anti-inflammatory drug (NSAID). Chemically, it
is 4-[4-(methylsulfony)phenyl]-3-phenyl-2(5H) furanone. Its
chemical structure contains two phenyl rings and a furanone
ring. It is believed to act by inhibition of prostaglandin
biosynthesis, through inhibition of the enzyme
cyclooxygenase-2 (COX-2); unlike
aspirin, it does not
inhibit cyclooxygenase-1.
[PJC]
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